Melting Point Determination and its Applications
This module reviews the basics of melting point determination, its applications, and the operation and best practices for its measurement
Basics of melting point determination including melting range, meniscus point and melting transitions
Factors influencing melting point
Relationship of melting point with the purity of the compound
Phase diagram and characterisation of material
Classification of melting point apparatus into apparatus I and apparatus II
Calibration of apparatus
Sample preparation
Components and operation of the melting point apparatus II and precautions to be taken when using it
Why it matters
Melting point is a characteristic feature of a substance based on its intrinsic properties. This parameter is used to characterize new products, measure purity, and in some cases, identify specific materials from a list of compounds. Understanding the science behind melting point determination can enable analysts to perform QC experiments correctly and get to the root cause of any errors.
Who is it for
This module is relevant to all new employees in analytical quality teams including quality control and quality assurance, who are involved in performing and reviewing the melting point method